Rochester’s Choice for Depression Treatment

Welcome to Nexus Neuropsychiatry, Rochester’s interventional psychiatry treatment center where we specialize in providing cutting-edge treatments. We provide a safe, welcoming environment where patients can access the latest advancements in psychiatric care.


If you’ve experienced unwanted side effects from your current medications or haven’t seen the results you hoped for, our advanced interventional therapies may be the right path forward:


  • TMS (Transcranial Magnetic Stimulation): A non-invasive, highly effective, drug-free treatment for depression and OCD.
  • Spravato (esketamine): An FDA-approved nasal spray specifically designed for those with treatment-resistant depression.
  • IV Ketamine: Rapid and powerful relief of symptoms from using novel mechanisms to target the glutamate system 
  • Vagus Nerve Stimulation: FDA-approved implanted device that treats depression around the clock


If you are in the Rochester area and feel your current treatment has stalled, we provide the specialized evaluation and advanced care needed to help you reclaim your life.


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Conditions Treated By Nexus Neuropsychiatry


In addition to adolescent, anxious, geriatric depression and OCD, we help people with TRD. When depression doesn’t respond to multiple treatment attempts, it may be considered treatment-refractory. We specialize in evaluating complex cases and offering advanced therapies—including medication adjustments, TMS, and esketamine—to help patients find relief and reclaim their lives.

If you reside in or near Rochester and are looking for help with depression, we can help. Especially if you've already tried multiple forms of medication and and are not seeing the results you expect.

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Schedule a Consultation

Looking for a local mental health expert? Get help today!


It's important to know that you are not alone.

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The Future of Mental Health


What does it really mean to show up for someone in crisis? In this powerful podcast episode, Dr. Shane Stegen of Nexus Neuropsychiatry, explores what healing looks like when life feels unmanageable. From his experience working with individuals facing depression, OCD, and trauma, Dr. Stegen brings honest insight into treatment options beyond medication, the importance of trust in therapy, and the emotional weight of supporting people at their lowest.


This isn't just a conversation about mental health — it’s a reminder of why compassion, presence, and curiosity are essential tools in the healing process.

Learn About TMS Therapy


How Depression Affects the Brain

During depression, the brain's emotional control center—the region responsible for mood regulation—operates at a diminished capacity. This center transmits vital signals along neural pathways to the areas of the brain that dictate how we act, react, and respond to various situations.


In a depressed brain, these neural pathways become underactive or even dormant. When these signals fail to fire correctly, the brain's natural ability to interpret, evaluate, and regulate emotions is impaired.


How TMS Therapy Restores Balance

Transcranial Magnetic Stimulation (TMS) is a non-invasive treatment that utilizes brief magnetic pulses to stimulate the specific brain regions impacted by depression.


Similar to strengthening a muscle through exercise, TMS encourages underactive neurons to begin firing and reconnecting. Over time, this stimulation helps restore the function of the emotional control center, allowing the brain to regulate mood naturally once again.


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Is TMS Therapy Right For You?


Do you feel sad, nervous, irritable, or restless? These symptoms are often related to depression and anxiety, two common mental health conditions. Monitoring the severity of your symptoms and how they fluctuate over time is an important step in seeking support.


We utilize brief, accessible online assessments to help you evaluate your mental health. By clicking the buttons below, you can take the PHQ-9 (for depressive symptoms) or the GAD-7 (for anxiety symptoms) we often use to help monitor your symptoms and progress.


Key Benefits For TMS Treatment


Transcranial Magnetic Stimulation (TMS) offers several key benefits as a treatment for clinical depression:

  • Non-Invasive and Convenient: TMS requires no surgery or anesthesia, allowing patients to immediately return to their daily activities following a session.
  • Safe and Well-Tolerated: TMS carries a very low risk of serious complications. Common side effects are mild and resolve quickly.
  • Clinically Proven and Effective: TMS serves as a powerful intervention for various conditions, offering life-saving results for those with Major Depressive Disorder (MDD).
  • Integrative and Flexible: TMS functions as a highly adaptable treatment, working alongside medication and psychotherapy to achieve the best possible outcomes.


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Patient Healing & Transformation Stories


Meet Oliver - TMS Therapy Testimonial

"I have hope", Oliver now says about his life after receiving TMS treatment. "I really honestly didn't expect much," says Oliver about TMS treatment. He was "grasping at straws" when he decided to try TMS treatment for his depression.

How TMS Helped Vickie With Depression

Vickie's depression was a "dark and lonely place" to be, and the medication she was on was not working. After receiving MagVenture TMS Therapy she is now in her own words "a happy happy person" who no longer suffer from depression.

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Why Choose Nexus Neuropsychiatry in Rochester?


We recognize that starting a mental health treatment can be a significant step for many individuals towards achieving their wellness goals. We also know that many hospitals and clinics can be a bit scary, sterile, or just a pain to get to. We aren’t like the big guys. Our office is located on the first floor of an office park with ample parking. There is no need to take as much time to park as it takes to attend your appointment! Walk into our suite, sit down, and relax in a place of healing.  We develop customized treatment plans based on your unique needs. You are certain to feel comfortable in our peaceful space while receiving the best care Rochester has to offer.

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Your Path To Mental Wellness Starts Here


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Submit an online form or contact us at (585) 201-8508

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Get back the life you were meant to live.