Spravato (Esketamine) Treatment
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TMS Therapy Supports Mental Wellness

  • Depression
  • Lack of Joy
  • Sadness and Despair
  • Low Mood
  • Lethargy
  • Insomnia
  • Oversleeping
  • Social Isolation
  • Self-Harm
  • Substance Abuse
  • Suicidal Ideation
  • Alcoholism

Spravato (Esketamine) Treatment

If you’ve been struggling with depression and traditional treatments haven’t worked, Spravato (esketamine) may be an option worth exploring. Spravato is an FDA-approved nasal spray specifically designed to treat treatment-resistant depression. Unlike conventional antidepressants, which primarily target serotonin pathways, Spravato works on different areas of the brain, providing faster relief for many patients.

One of the most exciting aspects of Spravato is that it can bring about improvements in symptoms within just a few hours or days—something many patients haven’t experienced with other medications. It’s administered in a controlled, clinical setting to ensure your safety and to closely monitor your response.

patients successfully treating depression with spravato

How Spravato Works

  • Mechanism of Action
     Spravato works by targeting the glutamate system in the brain, which plays a crucial role in mood regulation. Unlike traditional antidepressants, which take weeks to affect serotonin levels, Spravato acts on glutamate receptors, promoting rapid neuroplasticity—your brain’s ability to form new connections. This makes it especially effective for those who haven’t responded to other medications.

  • Comparison with Traditional Antidepressants
     Traditional antidepressants, like SSRIs or SNRIs, work by increasing serotonin levels over time, which can take weeks or months to show significant improvement. Spravato, however, begins to work within hours for many patients, making it a fast-acting option for those in need of immediate relief. It can be a lifeline, especially for individuals with suicidal thoughts or those who have not experienced success with previous treatments.


Who is Spravato For?

Spravato is specifically designed for people with treatment-resistant depression—those who have tried at least two other antidepressant medications without significant improvement. It is also indicated for individuals experiencing acute suicidal ideation, making it a powerful option for people in crisis.

  • Ideal Candidates Include:
  • Individuals diagnosed with treatment-resistant depression.
  • Those struggling with suicidal thoughts in the context of their depression.
  • Patients who haven’t responded to two or more traditional antidepressants.

Before starting Spravato, you will undergo a thorough interventional psychiatry consultation with us to ensure this treatment is the right fit for you. This includes a detailed psychiatric assessment and a review of your medical history to confirm Spravato is safe and the most appropriate next step in your treatment.

What to Expect During Spravato Treatment

  • Treatment Sessions
     Spravato is administered as a nasal spray in our office, under medical supervision. Your treatment plan will typically involve two sessions per week for the first four weeks, with a gradual tapering of the frequency over time as your symptoms improve. Each session lasts about two hours in total, which includes the time you’ll be monitored for safety after the spray is administered.

  • Patient Experience
     During each session, you’ll self-administer the nasal spray under our supervision. Afterward, you’ll stay in our comfortable treatment room for approximately two hours while we monitor you for any side effects or immediate reactions. Most patients report feeling relaxed or slightly drowsy during this time. You’ll need someone to drive you home after each session due to potential temporary effects like dizziness or mild dissociation.

  • Possible Side Effects
     Like all treatments, Spravato has potential side effects. The most common ones include dizziness, nausea, a floating sensation, or mild dissociation. These side effects typically wear off after the observation period. Rest assured, we take every precaution to ensure your experience is safe and comfortable.


Success Rates and Clinical Studies

  • Clinical Evidence
     The efficacy of Spravato has been backed by multiple clinical trials. In studies, many patients with treatment-resistant depression who received Spravato alongside an oral antidepressant showed significant improvement in their symptoms compared to those who continued with an oral antidepressant alone.

  • Patient Outcomes
     While every patient is different, many experience rapid relief of depressive symptoms within a few hours to days of starting treatment. For individuals who have been suffering from depression for years without relief, this can be life-changing. The combination of fast-acting relief and long-term improvement has made Spravato a powerful tool in the treatment of resistant depression.

Cost and Insurance Information

  • Cost of Spravato Treatment
     Spravato treatment involves more than just the medication itself—it also includes the monitoring and clinical oversight that’s essential for its safe administration. During your initial consultation, we’ll provide a clear cost breakdown based on the treatment plan we create for you.

  • Insurance Coverage
     Many insurance plans now cover Spravato for patients with treatment-resistant depression. We’re happy to work with your insurance company to verify your coverage. If Spravato isn’t fully covered by your plan, we’ll discuss out-of-pocket costs and any available financial assistance programs to ensure treatment is accessible. 
    We also partner with     CareCredit. (A health and wellness credit card with flexible financing options so you can pay over time for care.)


Contact Us for Spravato Treatment

If you or a loved one is suffering from treatment-resistant depression or experiencing suicidal thoughts, Spravato may offer the relief you’ve been searching for. We are here to help you determine if this groundbreaking treatment is right for you.

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